http://hdl.handle.net/1765/24578
http://dx.doi.org/10.1038/ng.386
pubmed: 19448620
scopus: 66649123583
http://dx.doi.org/10.1038/ng.386
pubmed: 19448620
scopus: 66649123583
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche
June 2009
Article
volume 41, issue 6 pp 648-650.
Repository contains one file which is not publicly available
We conducted a meta-analysis of genome-wide association data to detect genes influencing age at menarche in 17,510 women. The strongest signal was at 9q31.2 (P = 1.7 × 10 9), where the nearest genes include TMEM38B, FKTN, FSD1L, TAL2 and ZNF462. The next best signal was near the LIN28B gene (rs7759938; P = 7.0 × 10 9), which also influences adult height. We provide the first evidence for common genetic variants influencing female sexual maturation.