Identification and Functional Analysis of Genes Involved in Gliomagenesis
(Identificatie en functionele analyse van genen betrokken bij gliomagenese)
2011-12-14
Doctoral Thesis
| Related Files |
|---|
View PDF Version
(111214_Bralten, Linda Bianca Ciska.pdf, 12.2MB) |
|
View PDF Version
(Stellingen Bralten.pdf, 0.0MB) |
The median survival of glioma patient is still very poor and new therapeutic targets have to be discovered. The aim of this thesis is to identify genetic alterations in glioma and functionally characterize the most promising candidates. We describe several novel methods used to identify these mutations.
Supervisors
(promotores):
Keywords
Automatically Extracted Terms
- mutation
- glioma
- idh 1
- tumor
- caspr
- expression
- cancer
- idh 1 mutations
- sample
- non-p.r 132h mutations
- analysis
- chapter
- caspr 2 gene
- survival
- change
- glioblastoma
- caspr 2
- oligodendroglioma
- region
- isocitrate
