http://hdl.handle.net/1765/36012
http://dx.doi.org/10.3324/haematol.11493
pubmed: 18024410
scopus: 36348986709
http://dx.doi.org/10.3324/haematol.11493
pubmed: 18024410
scopus: 36348986709
Mutation analysis of the BRAF oncogene in juvenile myelomonocytic leukemia
November 2007
Article
volume 92, issue 11 pp 1574-1575.
Repository contains one file which is not publicly available
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative/ myelodysplastic disorder associated with mutations in the Ras-Raf-MEK-ERK- signaling pathway. B-Raf plays a central role in this pathway. In 65 screened JMML patients we identified no BRAF mutations and we conclude that this gene is unlikely to play a role in the pathogenesis of JMML.
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