Pig-to-Non-human Primate Heart Transplantation: Immunologic Progress Over 20 Years


Article
volume 26, issue 3 pp 210-218.
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The major developments in pig-to-non-human primate heart xenotransplantation during the past 20 years are summarized, largely through the experience of one investigator. Genetic modifications to organ-source pigs have been important steps in increasing heart xenograft survival from a few minutes in 1986 to 2 to 6 months in 2005.