Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study.
April 2004
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The purpose of this study was to assess the safety and effectiveness of sirolimus-eluting stent (SES) postdilatation with largely oversized balloons. We evaluated the clinical outcome of 68 consecutive patients enrolled in the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry who underwent percutaneous coronary intervention with SES implantation and further postdilatation with balloons > 1 mm larger than the stent nominal size. Angiographic follow-up was either scheduled for selected subgroups or clinically driven. Overall, 75 lesions were treated. The procedure was successful in 98.5% of the cases. One patient (1.5%) underwent emergency coronary bypass surgery for acute vessel occlusion. During 10.1 +/- 1.7 months of follow-up, three patients (4.5%) died, one (1.5%) had acute myocardial infarction, and four (6%) had target vessel revascularization. At angiographic follow-up, loss index was 0.13 +/- 0.34 and restenosis rate was 7.7%. Although not routinely recommended in every patient, SES postdilatation with largely oversized balloons appears a safe and effective strategy for selected patients.
- Male
- Aged
- Female
- Humans
- Netherlands/epidemiology
- Follow-Up Studies
- Middle Aged
- Treatment Outcome
- Equipment Design
- *Stents
- Ultrasonography, Interventional
- *Coronary Angiography
- Immunosuppressive Agents/*therapeutic use
- Sirolimus/*therapeutic use
- Blood Vessel Prosthesis Implantation
- Reoperation
- *Balloon Dilatation
- Coated Materials, Biocompatible/*therapeutic use
- Coronary Disease/diagnosis/therapy
- Coronary Restenosis/etiology/radiography/surgery
- Myocardial Infarction/diagnosis/therapy
- Platelet Glycoprotein GPIIb-IIIa Complex/therapeutic use
- Postoperative Complications/etiology/radiography/surgery