Arterial stiffness is known as an important surrogate marker of vascular damage and a strong predictor of cardiovascular disease (CVD). Age-related degenerative changes in the intima of large elastic arteries contribute to the loss of arterial elastin and to increased arterial stiffness.
Although arterial stiffness is strongly associated with ageing and is clinically shown mostly in older individuals, preclinical phases can occur in early childhood. [...]

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Journal European Journal of Preventive Cardiology
Ahmadizar, F, & Voortman, R.G. (2017). Arterial stiffness in childhood: A predictor for later cardiovascular disease?. European Journal of Preventive Cardiology. doi:10.1177/2047487317743046