In this chapter, we provide an overview of the background and state of the art in psychiatric genetics and genomics and its utility in the domains of scientific research as well as its practical application in the clinic. The field of psychiatric genetics and genomics has a history that spans more than 100 years and attempts to unravel the etiology of human mental illness. We describe the achievements and limitations of the work in this extensive period and provide an overview of the conceptual framework within which the genetic contribution to mental illness can be placed. Lastly, we reflect on the outstanding issues in the field.

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Keywords Gwas, Psychiatric genetic counseling, Schizophrenia, Whole exome sequencing
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Bouwkamp, C.G, Afawi, Z, & Kushner, S.A. (2019). Clinical genetic testing and counseling in psychiatry. In Clinical Genome Sequencing: Psychological Considerations (pp. 181–202). doi:10.1016/B978-0-12-813335-4.00011-8