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ORIGINAL ARTICLES VASCULAR SECTION
The Journal of Cardiovascular Surgery 2008 October;49(5):633-7
Copyright © 2008 EDIZIONI MINERVA MEDICA
language: English
The 30-day mortality of ruptured abdominal aortic aneurysms: influence of gender, age, diameter and comorbidities
Alexander S. 1, Bosch J. L. 2, 3, Hendriks J. M. 1, Visser J. J. 1, 2, 3, Van Sambeek M. R. H. M. 4
1 Department of Surgery/Vascular Surgery Erasmus University Medical Center Rotterdam, The Netherlands 2 Departments of Epidemiology and Biostatistics Erasmus University Medical Center Rotterdam, The Netherlands 3 Department of Radiology Erasmus University Medical Center Rotterdam, The Netherlands 4 Department of Surgery Catharina Hospital, Eindhoven, The Netherlands
Aim. The aim of this study was to determine the influence of gender, age, the aneurysm diameter and comorbidity on the 30-day mortality after open repair of ruptured abdominal aortic aneurysms (AAA).
Methods. Between January 1, 1993, and December 31, 2006 all consecutive patients who underwent open repair for a ruptured AAA at the tertiary care of Catharina teaching Hospital were included in this study (N=186). Patients who underwent endovascular repair of their ruptured abdominal aortic aneurysms were excluded from this study. Patient and procedure characteristics were collected and analyzed in relation to 30-day mortality. The association between age, gender, diameter of AAA and comorbidity with 30-day mortality was analyzed with c2 are and logistic regression; a P value <0.05 was considered significant.
Results. In this study there were 186 patients with ruptured AAA repair with an 30-day mortality of 36.6% (68/186). Among female patient 30-day mortality was 45.8% (11/24) compared with 35.2% (57/162) among male patients (P=0.31). Patients of 80 years and older had a 61.3% (19/31) 30-day mortality where younger patients had 33% (51/155) 30-day mortality (P=0.02). Thirty-day mortality was 47.2% (17/36) for patients with an AAA less than 65 mm compared with 34% (36/104) for patients with an AAA of 65 mm or larger (P=0.16). Multivariate analysis demonstrated age was a significant predictor of ruptured AAA repair mortality (P=0.017).
Conclusion. In this study, age was the only significant risk factor of 30-day mortality after open repair in patients with ruptured AAA.