A prospective subgroup analysis of two prospective, randomized, double-blind, placebo-controlled phase III clinical trials showed that the combination of lenalidomide plus dexamethasone is superior to dexamethasone alone in patients with relapsed or refractory multiple myeloma who had been previously treated with thalidomide; the implications for clinical practice are discussed.
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Meijer, E., Sonneveld, P. Lenalidomide plus dexamethasone is effective in multiple myeloma. Nat Rev Clin Oncol 6, 247–248 (2009). https://doi.org/10.1038/nrclinonc.2009.50
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DOI: https://doi.org/10.1038/nrclinonc.2009.50