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  • Special Report
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Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009

Bone Marrow Transplantation volume 45, pages 219–234 (2010)Cite this article

Abstract

The European Group for Blood and Marrow Transplantation regularly publishes special reports on the current practice of haematopoietic SCT for haematological diseases, solid tumours and immune disorders in Europe. Major changes have occurred since the first report was published. HSCT today includes grafting with allogeneic and autologous stem cells derived from BM, peripheral blood and cord blood. With reduced-intensity conditioning regimens in allogeneic transplantation, the age limit has increased, permitting the inclusion of older patients. New indications have emerged, such as autoimmune disorders and AL amyloidosis for autologous HSCT and solid tumours, myeloproliferative syndromes and specific subgroups of lymphomas for allogeneic transplants. The introduction of alternative therapies, such as imatinib for CML, has challenged well-established indications. An updated report with revised tables and operating definitions is presented.

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Acknowledgements

We are grateful for the advice and helpful comments received from a number of individuals across Europe specializing in the use of haematopoietic stem cell transplantation. Special thanks to C Morris, M Mohty, C Schmid, R Willemze, J Esteve, A Nagler, S Giebel, P Corradini, P Dreger, E Olavarria, D Farge, C Gisselbrecht, H Greinix, Y Beguin, CG Steward, A Fischer, A Cant, L Notarangelo, W Friedrich, I Yaniv, R Ladenstein, N Schmitz, S Montoto, O Hermine and N Wulffraat.

Author information

Authors and Affiliations

  1. Department of Haematology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

    P Ljungman

  2. Unit of Medical Oncology, San Giuseppe Hospital, Milan, Italy

    M Bregni

  3. Department of Medicine, Section of Haematology, Sahlgren's University Hospital, Göteborg, Sweden

    M Brune

  4. Department of Hematology, Erasmus MC-Daniel den Hoed Cancer Centre, Rotterdam, The Netherlands

    J Cornelissen

  5. Department of Hematology, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands

    T de Witte

  6. Department of Paediatric Haematology and Oncology, IRCCS ‘G.Gaslini’, Genoa, Italy

    G Dini

  7. Department of Haematology and Oncology, University of Würzburg, Würzburg, Germany

    H Einsele

  8. Molecular Immunology Unit, UCL Institute of Child Health, London, UK

    H B Gaspar

  9. Haematology Division, University Hospital, Basel, Switzerland

    A Gratwohl & A Tichelli

  10. Haematology Division, Geneva University Hospital, Geneva, Switzerland

    J Passweg

  11. BMT Unit, St Anna Kinderspital, Vienna, Austria

    C Peters

  12. Department of Haematology and Eurocord office, BMT Unit, Hôpital St Louis, Paris, France

    V Rocha

  13. Department of Haematology, Careggi Hospital & University of Florence, Florence, Italy

    R Saccardi

  14. Department of Internal Medicine, Section of Haematology, University Hospital, Maastricht, The Netherlands

    H Schouten

  15. Clinical Haematology Division, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

    A Sureda

  16. Department of Haematology, University of Perugia, P, erugia, Italy

    A Velardi

  17. Department of Haematology and Oncology, University of Leipzig, Leipzig, Germany

    D Niederwieser

Authors
  1. P Ljungman
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  2. M Bregni
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  3. M Brune
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  4. J Cornelissen
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  5. T de Witte
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  6. G Dini
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  7. H Einsele
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  8. H B Gaspar
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  9. A Gratwohl
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  10. J Passweg
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  11. C Peters
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  12. V Rocha
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  13. R Saccardi
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  14. H Schouten
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  15. A Sureda
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  16. A Tichelli
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  17. A Velardi
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  18. D Niederwieser
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for the European Group for Blood and Marrow Transplantation

Corresponding author

Correspondence to P Ljungman.

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Ljungman, P., Bregni, M., Brune, M. et al. Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe 2009. Bone Marrow Transplant 45, 219–234 (2010). https://doi.org/10.1038/bmt.2009.141

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  • DOI: https://doi.org/10.1038/bmt.2009.141

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