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Functional parameters of the left ventricle: comparison of cardiac MRI and cardiac CT in a large population

Parametri funzionali del ventricolo sinistro: confronto tra cardio-RM e cardio-TC in un’ampia popolazione

  • Cardiac Radiology/Cardioradiologia
  • Published:
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Abstract

Purpose

The authors sought to compare magnetic resonance imaging (MRI) and computed tomography (CT) for assessing left ventricular (LV) function parameters in a large patient population.

Materials and methods

The study was conducted on 181 patients who underwent cardiac MRI and cardiac CT for various indications. For MRI, we used two-dimensional cine balanced steady-state free precession (b-SSFP) sequences, and for CT we used multiphase short-axis reconstructions. Volume data sets were evaluated with dedicated software. Results were compared with a paired, two-tailed Student’s t test, Pearson’s correlation (r), and Bland-Altman analysis.

Results

A high level of concordance was observed between cardiac MRI and CT. Ejection fraction (EF) was 53±14% for MRI vs. 53%±15% for CT. There was good correlation for EF (r=0.71; p>0.05) and end-systolic volume (r=0.74; p>0.05). End-diastolic volume (74±23 ml at MRI vs. 71±19 ml at CT; r=0.58; p<0.05) and myocardial mass (63±20 g at MRI and 56±18 g at CT; r=0.89; p<0.01) showed statistically significant differences, although the discrepancy had no clinical impact.

Conclusions

MRI and CT show a good level of agreement in assessing LV function parameters, and both can be used interchangeably in clinical practice.

Riassunto

Obiettivo

Obiettivo di questo lavoro è stato confrontare la risonanza magnetica (RM) e la tomografia computerizzata (TC) per la valutazione dei parametri funzionali del ventricolo sinistro (Vsin) in una vasta popolazione di pazienti.

Materiali e metodi

Sono stati arruolati 181 pazienti che sono stati sottoposti ad esame cardio-RM e cardio-TC. Per la cardio-RM abbiamo utilizzato sequenze 2D cine b-steady-state free-precession (SSFP) e per la TC abbiamo utilizzato delle ricostruzioni multifasiche in asse corto. I data-set di volume sono stati analizzati con un software dedicato: Argus (versione Va60C). I risultati sono stati confrontati con il test t di Student a due code per dati appaiati, la correlazione di Pearson ed l’analisi di Bland-Altman.

Risultati

È stata osservata una elevata concordanza tra la cardio-RM e la cardio-TC. La frazione di eiezione (FE) è stata 53%±14% per la RM e 53%±15% per la TC. Buona correlazione è stata osservata per la FE (r=0,71; p>0,05) e per il volume tele-sistolico (VTS) (r=0,74; p>0,05). Il volume tele-diastolico (74±23 ml per RM e 71±19 ml per TC; r=0,58; p<0,05) e la massa miocardica (63±20 g per RM e 56±18 g per TC; r=0,89; p<0,01) hanno dimostrato differenze statisticamente significative anche se prive di impatto clinico.

Conclusioni

Gli esami cardio-RM e cardio-TC mostrano una eccellente concordanza per la valutazione dei parametri funzionali del Vsin e possono quindi essere utilizzati indifferentemente nella pratica clinica.

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Authors and Affiliations

  1. Dipartimento di Radiologia e Cardiologia, Azienda Ospedaliero-Universitaria, Parma, Italy

    A. Palumbo, E. Maffei, C. Martini, S. Seitun, A. Aldrovandi, E. Emiliano, A. Cuttone & F. Cademartiri

  2. Radiology and Cardiology Department, Erasmus Medical Centre, Rotterdam, The Netherlands

    A. Palumbo, A. Weustink, N. Mollet & F. Cademartiri

  3. Dipartimento di Radiologia, Università degli Studi di Napoli “Federico II”, Napoli, Italy

    G. Messalli

  4. Dipartimento di Radiologia, SDN Fondazione IRCCS, Napoli, Italy

    G. Messalli

  5. Dipartimento di Radiologia, Università di Verona, Verona, Italy

    R. Malagò

  6. Dipartimento di Radiologia e Diagnostica per Immagini, c/o Piastra Tecnica - Piano 0, Azienda Ospedaliero-Universitaria, Via Gramsci 14, 43100, Parma, Italy

    F. Cademartiri

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  1. A. Palumbo
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  2. E. Maffei
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  8. E. Emiliano
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Correspondence to F. Cademartiri.

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Palumbo, A., Maffei, E., Martini, C. et al. Functional parameters of the left ventricle: comparison of cardiac MRI and cardiac CT in a large population. Radiol med 115, 702–713 (2010). https://doi.org/10.1007/s11547-010-0525-0

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  • DOI: https://doi.org/10.1007/s11547-010-0525-0

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