CommentCytotoxic T lymphocyte memory: role in cross-protective immunity against influenza?
References (36)
- et al.
Vaccination and protection from a lethal virus infection: identification, incorporation and use of a cytotoxic T lymphocyte glycoprotein epitope
Virology
(1990) - et al.
Cell biology of antigen processing and presentation to major histocompatibility complex class I molecule-restricted T lymphocytes
Adv. Immunol.
(1992) - et al.
Efficacy of nucleoprotein and haemagglutinin antigens expressed in fowlpox virus as vaccine for influenza in chickens
Vaccine
(1991) - et al.
Roles of αβ and γ T cell subsets in viral immunity
Annu. Rev. Immunol.
(1992) - et al.
Clearance of persistent respiratory syncytial virus infection in immunodeficient mice following transfer of primed T cells
Virology
(1987) - et al.
CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity
J. Virol.
(1987) - et al.
Cooperation between cytotoxic and helper T lymphocytes in protection against a lethal sendai virus infection
J. Exp. Med.
(1986) - et al.
Recovery from acute virus infection
Ann. NY Acad. Sci.
(1988) - et al.
Cytotoxic T cell in influenza infection
Ann. NY Acad. Sci.
(1988) - et al.
Transfer of specific cytotoxic T cells protects mice inoculated with influenza viruses
Nature
(1978)
The predominance of CD8+ cells after infection with measles virus suggests a role for CD8+ class I MHC-restricted cytotoxic T lymphocytes (CTL) in recovery from measles. Clonal analyses of human CD8+ class I MHC restricted CTL
J. Immunol.
The influenza A virus nucleoprotein gene controls the induction of both subtype specific and cross-reactive cytotoxic T cells
J. Exp. Med.
Influenza A virus nucleoprotein is a major target antigen for crossreactive antiinfluenza A virus cytotoxic T lymphocytes
Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes
J. Exp. Med.
Orthomyxoviruses
Primary pulmonary cytotoxic T lymphocytes induced by immunization with a vaccinia virus recombinant expressing influenza A virus nucleoprotein peptide do not protect mice against challenge
J. Virol.
β2-Microglobulin-deficient mice can be protected against influenza A infection by vaccination with vaccinia-influenza recombinants expressing hemaglutinin and neuraminidase
J. Immunol.
The roles of influenza virus hemaglutinin and nucleoprotein in protection: analysis using vaccinia virus recombinants
Scand. J. Immunol.
Cited by (34)
Respiratory Virus Vaccines
2015, Mucosal Immunology: Fourth EditionImmune responses to influenza virus infection
2011, Virus ResearchCitation Excerpt :It was suggested that also functional constraints may limit influenza viruses to escape efficiently from recognition by CTL specific for highly conserved epitopes (Berkhoff et al., 2005, 2006). The immune response induced by influenza A virus infection can to a certain extent provide protection against subsequent infections with an influenza A virus of another subtype (Grebe et al., 2008; Rimmelzwaan and Osterhaus, 1995). This so-called heterosubtypic immunity depends on the cross-reactivity of antibodies and especially T cells.
Influenza virus-specific cytotoxic T lymphocytes: a correlate of protection and a basis for vaccine development
2007, Current Opinion in BiotechnologyCitation Excerpt :Other evidence in support of a protective role of CTL was obtained by vaccination aiming at the induction of CTL responses to the conserved internal viral proteins. Protective CTL responses were achieved especially by vaccination with plasmid DNA from which the NP gene was expressed [24•,25–27], but also by vaccination with NP subunit preparations [28–31], while the use of recombinant vaccinia viruses expressing the influenza virus NP gene was relatively inefficient [32]. The evidence for a protective role for CTL in humans is sparse and in most cases circumstantial.