Herpes simplex virus type 1 (HSV-1) is a common cause of ocular diseases, affecting all parts of the visual axis. HSV-1 keratitis and uveitis represent two prevalent ocular diseases. The outcome of these potentially sightthreatening conditions depends on prompt diagnosis and treatment in order to counteract the detrimental intra-ocular virus-host interaction. This review recapitulates current insights on the diagnosis, pathogenesis, and treatment of HSV-1 keratitis and uveitis in patients and in the respective mouse models.

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doi.org/10.2174/157339511796196557, hdl.handle.net/1765/63413
Current Immunology Reviews
Department of Virology

Verjans, G.M.G.M, & Heiligenhaus, A. (2011). Herpes simplex virus-induced ocular diseases: Detrimental interaction between virus and host. Current Immunology Reviews (Vol. 7, pp. 310–327). doi:10.2174/157339511796196557