The effect of reduced blood-flow on the coronary wall temperature. Are significant lesions suitable for intravascular thermography?
AIMS: The purpose of this study was to investigate the relation between acute coronary flow reduction and arterial wall temperature. METHODS AND RESULTS: Five pigs with normal coronary arteries were catheterized. Arterial wall temperature was studied with a thermographic system that uses a 4-thermistor sensor tip. Flow velocity was studied at the same time and place with the temperature measurements, using a Doppler wire. In order to modify the coronary flow, a balloon was gradually inflated proximally to the thermographic sensors. Temperature differences and flow velocities were simultaneously recorded.Flow velocities above an average peak velocity (APV) of 9 cm/s were associated with unaffected temperature measurements. At flow velocities around 4 cm/s, the wall temperature was increased (deltaT=0.015+/-0.005 degrees C, P approximately 0.05), following the heart-rate. When flow velocity dropped further below this value, the local wall temperature was logarithmically increased to a maximum value observed at total vessel occlusion (deltaT=0.188+/-0.023 degrees C, P<0.001). CONCLUSION: The reduction of coronary flow has an effect on the arterial wall temperature. This effect however, appears only below a critical threshold of APV and in a logarithmic fashion. Above this threshold, temperature measurements should be unaffected from flow reductions and related to the regional temperature heterogeneity.
|Keywords||Animals, Arteries, Blood Flow Velocity/physiology, Body Temperature/*physiology, Coronary Circulation/*physiology, Coronary Vessels/*physiology, Swine, Thermography/methods, flow, inflammation, temperature, vulnerable|
|Persistent URL||dx.doi.org/10.1016/S0195-668X(03)00440-8, hdl.handle.net/1765/10232|
Diamantopoulos, L., Liu, X., de Scheerder, I.K., Li, S., van Cleemput, J., Desmet, W., … Krams, R.. (2003). The effect of reduced blood-flow on the coronary wall temperature. Are significant lesions suitable for intravascular thermography?. European Heart Journal, 24(19), 1788–1795. doi:10.1016/S0195-668X(03)00440-8