Two-dimensional echocardiography is a commonly used non-invasive method for the assessment of left ventricular function. It provides precise information on both global and segmental myocardial function by displaying endocardial motion and wall thickening. Dobutamine stress echocardiography (DSE) is currently the leading non-invasive imaging technique for the diagnosis and prognosis of coronary artery disease (CAD), the documentation of myocardial viability and for long-term risk stratification [1]. The term clinical stress echocardiography is starting to be applied as DSE is used in different clinical settings.