The epidemiology and risks of Staphylococcus aureus carriage in continuous peritoneal dialysis (CPD) patients was studied in a single tertiary-care institution. On outpatient visits samples for culture were routinely taken prospectively from the CPD catheter exit site and the vestibulum nasi. Seventy-five patients with at least one culture positive for S. aureus in this period were included: 43 had genotypically identical S. aureus strains in over 80% of the cultures and were classified as persistent carriers; 32 were intermittent carriers. Persistent carriage was associated with a threefold higher risk for CPD-related infections and sixfold higher rates of vancomycin consumption compared to those for the intermittent carriers. No methicillin or vancomycin resistance was detected.

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Keywords Adolescent, Adult, Aged, Carrier State/*epidemiology/*microbiology, Female, Humans, Male, Middle aged, Nose/microbiology, Peritoneal Dialysis, Continuous Ambulatory/*adverse effects, Risk Factors, Staphylococcal Infections/*epidemiology/microbiology, Staphylococcus aureus/*isolation & purification
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Nouwen, J.L., Schouten, J., Schneebergen, P., Snijders, S.V., Maaskant, J., Koolen, M., … Verbrugh, H.A.. (2006). Staphylococcus aureus carriage patterns and the risk of infections associated with continuous peritoneal dialysis.. Journal of Clinical Microbiology, 44(6), 2233–2236. doi:10.1128/JCM.02083-05