The spliceosome as target for anticancer treatment
The spliceosome is a ribonucleoprotein complex involved in RNA splicing, that is, the removal of non-coding introns from precursor messenger RNA. (Alternative) Splicing events may play an essential role in tumourigenesis. The recent discovery that the spliceosome is a target for novel compounds with anticancer activity opens up new therapeutic avenues.British Journal of Cancer advance online publication, 25 November 2008; doi:10.1038/sj.bjc.6604801 www.bjcancer.com.
|Persistent URL||dx.doi.org/10.1038/sj.bjc.6604801, hdl.handle.net/1765/14194|
van Alphen, R.J., Wiemer, E.A.C., Burger, H., & Eskens, F.A.L.M.. (2008). The spliceosome as target for anticancer treatment. British Journal of Cancer, 100(2), 228–232. doi:10.1038/sj.bjc.6604801