The clinical utility of stress testing in patients without angina pectoris after revascularization has been questioned. Dobutamine stress echocardiography (DSE) is an established technique for detection of myocardial ischemia and cardiac risk stratification. We studied the prognostic value of DSE in 393 patients without typical angina pectoris after coronary revascularization. Ischemia was incremental to clinical data in predicting all-cause death (hazard ratio 3.5, 95% confidence interval 1.8 to 6.7) and cardiac death (hazard ratio 4.2, 95% confidence interval 1.8 to 9.8). In conclusion, myocardial ischemia during DSE is independently associated with an increased risk of all-cause mortality and cardiac death in these patients after adjustment for clinical data.

Additional Metadata
Keywords Adult, Aged, Female, angina pectoris, article, exercise test, heart muscle ischemia, heart muscle revascularization, human, major clinical study, male, mortality, priority journal, prognosis, stress echocardiography
Persistent URL dx.doi.org/10.1016/j.amjcard.2008.06.040, hdl.handle.net/1765/14478
Citation
Pedone, C., Elhendy, A., Biagini, E., van Domburg, R.T., Schinkel, A.F.L., di Pasquale, G., … Poldermans, D.. (2008). Prognostic Significance of Myocardial Ischemia by Dobutamine Stress Echocardiography in Patients Without Angina Pectoris After Coronary Revascularization. The American Journal of Cardiology, 102(9), 1156–1158. doi:10.1016/j.amjcard.2008.06.040