In the absence of a fixed relationship between plaque vulnerability and flow-limiting stenosis, alternative morphological expressions exist that could predict the liability of coronary lesions to rapidly progress or rupture, causing acute coronary syndromes. Modern multidetector computed tomography technology is capable of noninvasively detecting lesion location, attenuation, remodeling and calcification pattern, which may be considered as surrogate morphological markers of vulnerability and could contribute to increase the prognostic value of individual coronary plaque burden.

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Keywords Computed tomography, Intravascular ultrasound, Plaque remodeling, Vulnerable plaque, acute coronary syndrome, atherosclerotic plaque, blood vessel calcification, cardiovascular risk, coronary artery atherosclerosis, course evaluation, diagnostic value, high risk patient, human, image analysis, intracoronary ultrasound, intravascular ultrasound, lipid composition, minimally invasive procedure, multidetector computed tomography, review, risk assessment, tissue structure
Persistent URL dx.doi.org/10.2459/JCM.0b013e32832e8ce5, hdl.handle.net/1765/17903
Citation
Pugliese, F., Meijboom, W.B., Ligthart, J.M.R., la Grutta, L., Vourvouri, E.C., Rodriguez-Granillo, G.A., … Cademartiri, F.. (2009). Parameters for coronary plaque vulnerability assessed with multidetector computed tomography and intracoronary ultrasound correlation. Journal of Cardiovascular Medicine (Hagerstown), 10(11), 821–826. doi:10.2459/JCM.0b013e32832e8ce5