A 56-year-old female, originally from Suriname, with an otherwise unremarkable previous medical history was found to have a renal mass highly suspicious for renal cancer for which a nephrectomy was performed. Within the kidney, a tumourous mass was found which, on histological examination, showed an inflammatory pseudotumour caused by Histoplasma capsulatum. Further investigations revealed an idiopathic CD4+ lymphopenia. Mass lesions mimicking a malignant tumour caused by infection with Histoplasma have rarely been described. To the best of our knowledge, this is the first report of a Histoplasma-associated inflammatory pseudotumour mimicking cancer occurring in the kidney.

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Keywords CD4 antigen, Histoplasma, Histoplasma capsulatum, Immunodeficiency, Inflammatory pseudotumour, Kidney neoplasms, Suriname, adult, article, case report, female, histopathology, human, human tissue, kidney cancer, kidney carcinoma, laboratory test, lymphocytopenia, nephrectomy, plasma cell granuloma, priority journal
Persistent URL dx.doi.org/10.1007/s00428-008-0714-6, hdl.handle.net/1765/19335
Citation
den Bakker, M.A., Goemaere, N.N.T., Severin, J.A., Nouwen, J.L., & Verhagen, P.C.M.S.. (2009). Histoplasma-associated inflammatory pseudotumour of the kidney mimicking renal carcinoma. Virchows Archiv, 454(2), 229–232. doi:10.1007/s00428-008-0714-6