Pulmonary hypoplasia is a condition characterized by a decrease in the number of lung cells, airways and alveoli with a resulting decrease in organ size and weight. The reported incidence of pulmonary hypoplasia in the general population is about 1 per 1000 live births and it is one of the most common single abnormalities found at postmortem examination. The occurrence of pulmonary hypoplasia is mostly secondary to congenital anomalies or pregnancy complications that inhibit lung development. For instance prolonged oligohydramnios due to premature rupture of membranes (PROM) or fetal renal and urinary tract malformations may lead to abnormal fetal lung development with subsequent severe respiratory distress immediately after birth and even neonatal death.

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J.E. Jurriaanse Stichting, Laudy Bouw Groep BV, Organon Nederland BV, Schering Nederland BV, Toshiba Medical Systems Europe BV
J.W. Wladimiroff (Juriy)
Erasmus University Rotterdam
hdl.handle.net/1765/20423
Erasmus MC: University Medical Center Rotterdam

Laudij, J. (2000, November 15). Doppler ultrasonography of the human fetal pulmonary circulation. Retrieved from http://hdl.handle.net/1765/20423