Anti-Müllerian hormone and androgens: regulation of receptors during sex differentiation and gonadal development

This chapter gives an outline of sex determination, sex differentiation, and gonadal development in mammalian species. In most studies described herein, rats and mice were used. During embryonal development in mammals, sex differentiation is preceded by a bipotential stage. Indifferent gonads are formed that can develop into eilher testes or ovaries. The anlagen of the male and female intemal genitalia, which are both present in embryos of either chromosomal sex, are called the wolffian and the mullerian ducts, respectively.