Primary Biliary Cirrhosis (PBC) is a chronic, cholestatic liver disease characterized by non-suppurative destruction of interlobular and septal bile ducts, with subsequent liver damage and eventually development of cirrhosis. The disease is relatively rare with an estimated annual incidence and point prevalence in Europe of about 14 and 114 per million population respectively.The course of the disease is variable and unpredictable, but potentially fa1tal.

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Zambon Nederland BV
G.P. van Berge Henegouwen (Gerard) , S.W. Schalm (Solko)
Erasmus University Rotterdam , Babeliowsky, Amsterdam
hdl.handle.net/1765/21997
Erasmus MC: University Medical Center Rotterdam

Wolfhagen, F. (1995, September 20). Bile acid and immunosuppressive therapy in primary biliary cirrhosis. Retrieved from http://hdl.handle.net/1765/21997