Malformations of the Human Cerebral Cortex: patterns and causes
Malformations of cortical development (MCD) are a group of disorders characterized by a congenital abnormal structure of the cerebral cortex. In general, malformations are defined as structural abnormalities caused by a disturbance in cell organization or function within a tissue type. When a disturbance results in an abnormal structure of the cerebral cortex we call this: malformations of cortical development. MCD are heterogeneous as a group, as they include several different structural abnormalities, and they have a diverse array of causes, both genetic and environmental.
|Keywords||MCD, congenital malformations, disorders, malformations of the cerebral cortex|
|Promotor||Arts, W.F.M. (Willem Frans) , Grosveld, F.G. (Frank)|
|Publisher||Erasmus University Rotterdam|
|Sponsor||Erasmus MC Rotterdam, UCB Pharma B.V., Cyberonics Europe N.V., Sanofi-Aventis Netherlands B.V.|
de Wit, M.C.Y.. (2010, September 10). Malformations of the Human Cerebral Cortex: patterns and causes. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/22639