Diminished contractile function may occur in regional myocardium or present itself as global hypokinesis. Abnormality in contractile function of regional myocardium is usually the result of ischemia with or without subsequent restoration of blood flow, while global hypokinesis is often seen in congestive heart failure. Experimental investigations, however, have implicated that, among other factors, an abnonnality in excitation contraction coupling of the myocardium could serve as a potential mechanism for both regional and global contractile abnormality.

Additional Metadata
Keywords cardiology, heart failure
Promotor P.D. Verdouw (Pieter) , P.P. de Tombe
Publisher Erasmus University Rotterdam
Sponsor Netherlands Heart Foundation
ISBN 978-909009-885-2
Persistent URL hdl.handle.net/1765/22731
Citation
Fan, D.. (1996, November 27). Modulation of determinants of myocardial function and energetics by stunning and heart failure. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/22731