Objective. Intramural hematoma of the small intestine is a complication of anticoagulant treatment with an estimated incidence of 1 case per 2500 anticoagulated patients per year. Patients may present with signs of small bowel obstruction or, in case of a ruptured hematoma, with upper gastrointestinal tract hemorrhage and hypovolemic shock. Material and methods. Case report and review of the literature. Results. We present a case of a 73-year-old male who was referred for a protruding mass in the duodenum and subsequently developed hematemesis and melena caused by a ruptured hematoma of the duodenal wall. Conclusions. Although intramural hematoma of the duodenum is a rare complication of anticoagulant therapy, early diagnosis with subsequent correction of coagulation parameters is of vital importance.

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doi.org/10.3109/00365521.2010.531484, hdl.handle.net/1765/22769
Scandinavian Journal of Gastroenterology
Erasmus MC: University Medical Center Rotterdam

Veldt, B., Haringsma, J., Florijn, K., & Kuipers, E. (2011). Coumarin-induced intramural hematoma of the duodenum: Case report and review of the literature. Scandinavian Journal of Gastroenterology, 46(3), 376–379. doi:10.3109/00365521.2010.531484