Cushing syndrome as the presenting symptom of a malignant renal tumor in children is rare. We report the first case of paraneoplastic Cushing syndrome due to a Wilms tumor, in which clinical and biological signs of hypercortisolism regressed during preoperative chemotherapy. Additionally, we reviewed the literature on paraneoplastic Cushing syndrome secondary to pediatric renal tumors.

Additional Metadata
Keywords Adrenocorticotropic hormone (ACTH), Corticotrophin-releasing hormone (CRH), Cushing syndrome, Nephroblastoma, Renal tumor
Persistent URL dx.doi.org/10.1002/pbc.22021, hdl.handle.net/1765/24111
Citation
Segers, H, van der Heyden, J.C, van den Akker, E.L.T, de Krijger, R.R, Zwaan, C.M, & van den Heuvel-Eibrink, M.M. (2009). Cushing syndrome as a presenting symptom of renal tumors in children. Pediatric Blood & Cancer, 53(2), 211–213. doi:10.1002/pbc.22021