1988
The transcriptional unit of the murine Thy-1 gene unit: Differential distribution of transcription initiation sites in brain.
Publication
Publication
Molecular and Cellular Biology , Volume 8 p. 3847- 3856
Structural analysis of the mouse Thy-1.2 gene has shown that the major promoter of the gene is characterized by a tissue-specific DNase I-hypersensitive site and is located within a methylation-free island. The gene is regulated at the transcriptional level, and steady-state mRNA analysis reveals that the previously reported exon Ib contributes at most 5% of the total mRNA. The major promoter uses several transcription initiation sites within a region of 100 base pairs. The frequency of usage of these sites in brain is markedly different from that in other tissues.
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hdl.handle.net/1765/2429 | |
Molecular and Cellular Biology | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Spanopoulou, E., Giguere, V., & Grosveld, F. (1988). The transcriptional unit of the murine Thy-1 gene unit: Differential distribution of transcription initiation sites in brain. Molecular and Cellular Biology, 8, 3847–3856. Retrieved from http://hdl.handle.net/1765/2429 |