First case of stenting of a vulnerable plaque in the SECRITT I trial-the dawn of a new era?
BACKGROUND: A 63-year-old man presented with class II anginal symptoms. INVESTIGATIONS: Cardiac catheterization, intravascular ultrasound (IVUS) virtual histology, optical coherence tomography and off-line palpography. DIAGNOSIS: The patient was diagnosed as having a culprit lesion in the left circumflex artery and a vulnerable plaque in the left anterior descending artery. MANAGEMENT: The culprit lesion was treated with two overlapping drug-eluting stents. The vulnerable plaque was then treated with a self-expanding stent tailored to shield vulnerable plaques (vProtect Luminal Shield). After dilatation of the stent with a low-pressure balloon, IVUS and optical coherence tomography showed excellent apposition of the stent to the vessel wall, with no signs of tissue prolapse or edge dissections. At the 6-month follow-up appointment, the stent showed complete tissue coverage without signs of in-stent restenosis. CONCLUSIONS: Six months of follow-up has demonstrated that a patient with an IVUS-derived, thin capped fibroatheroma was successfully treated with a stent tailored to shield vulnerable plaques.
|Persistent URL||dx.doi.org/10.1038/nrcardio.2009.34, hdl.handle.net/1765/24588|
|Journal||Nature Reviews Cardiology|
Ramcharitar, S, Gonzalo, N, van Geuns, R.J.M, Garcia-Garcia, H.M, Wykrzykowska, J.J, Ligthart, J.M.R, … Serruys, P.W.J.C. (2009). First case of stenting of a vulnerable plaque in the SECRITT I trial-the dawn of a new era?. Nature Reviews Cardiology, 6(5), 374–378. doi:10.1038/nrcardio.2009.34