Genes predict village of origin in rural Europe
The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.
|Keywords||genome-wide genotyping, population structure, principal components|
|Persistent URL||dx.doi.org/10.1038/ejhg.2010.92, hdl.handle.net/1765/28257|
|Journal||European Journal of Human Genetics|
|Note||Free full text at PubMed|
O'Dushlaine, C, McQuillan, R, Weale, M.E, Crouch, D.J.M, Johansson, A, Aulchenko, Y.S, … Wilson, J.F. (2010). Genes predict village of origin in rural Europe. European Journal of Human Genetics, 18(11), 1269–1270. doi:10.1038/ejhg.2010.92