The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations. Copyright

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Journal The European Respiratory Journal
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Cazzola, M, MacNee, W, Martinez, F.J, Rabe, K.F, Franciosi, L.G, Barnes, P.J, … Wouters, E.F.M. (2008). Outcomes for COPD pharmacological trials: From lung function to biomarkers. The European Respiratory Journal, 31(2), 416–468. doi:10.1183/09031936.00099306