The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations. Copyright

doi.org/10.1183/09031936.00099306, hdl.handle.net/1765/30024
The European Respiratory Journal
Erasmus MC: University Medical Center Rotterdam

Cazzola, M., MacNee, W., Martinez, F. J., Rabe, K. F., Franciosi, L. G., Barnes, P. J., … Wouters, E. (2008). Outcomes for COPD pharmacological trials: From lung function to biomarkers. The European Respiratory Journal (Vol. 31, pp. 416–468). doi:10.1183/09031936.00099306