Sublingual immunotherapy in children with allergic rhinitis
Allergic rhinitis is one of the most prevalent chronic diseases in Europe. Besides nose symptoms such as sneezing and a blocked nose, patients also suffer from general complaints like fatigue, sleeping problems and difficulty concentrating. Allergic rhinitis can have a serious impact on the daily life of children, because it interferes with their social activities, hobbies and schoolwork. Allergen avoidance and symptomatic treatment will only result in short-term relief. Allergen-specific immunotherapy on the other hand, targets the cause of the disease and can induce long-term remission of the allergic symptoms. This thesis presents an overview of the evidence for the efficacy of immunotherapy in children with allergic rhinitis and the results of the STARDROP-study. In this study the clinical efficacy, immunological effects and adherence to sublingual immunotherapy (SLIT) with a grass pollen extract in children with hay fever were investigated.
|Publisher||Erasmus MC: University Medical Center Rotterdam|
|Promotor||Berger, M.Y. (Marjolein) , Gerth van Wijk, R. (Roy)|
|Sponsor||The STARDROP-study was funded by Artu Biologicals (main sponsor) and Stichting Astma Bestrijding|
|Keywords||allergic rhinitis, children, sublingual immunotherapy|
Röder, E.. (2012, February 29). Sublingual immunotherapy in children with allergic rhinitis. Erasmus MC: University Medical Center Rotterdam. Retrieved from http://hdl.handle.net/1765/31635