In search of hidden Q-fever outbreaks: Linking syndromic hospital clusters to infected goat farms
Large Q-fever outbreaks were reported in The Netherlands from May 2007 to 2009, with dairy-goat farms as the putative source. Since Q-fever outbreaks at such farms were first reported in 2005, we explored whether there was evidence of human outbreaks before May 2007. Space-time scan statistics were used to look for clusters of lower-respiratory infections (LRIs), hepatitis, and/or endocarditis in hospitalizations, 2005-2007. We assessed whether these were plausibly caused by Q fever, using patients' age, discharge diagnoses, indications for other causes, and overlap with reported Q fever in goats/humans. For seven detected LRI clusters and one hepatitis cluster, we considered Q fever a plausible cause. One of these clusters reflected the recognized May 2007 outbreak. Real-time syndromic surveillance would have detected four of the other clusters in 2007, one in 2006 and two in 2005, which might have resulted in detection of Q-fever outbreaks up to 2 years earlier.
|Keywords||Outbreaks, Q fever, respiratory infections, surveillance, zoonoses|
|Persistent URL||dx.doi.org/10.1017/S0950268810001032, hdl.handle.net/1765/34104|
van den Wijngaard, C., Dijkstra, F., van Pelt, W., van Asten, L., Kretzschmar, M., Schimmer, B., … Koopmans, M.P.G., D.V.M.. (2011). In search of hidden Q-fever outbreaks: Linking syndromic hospital clusters to infected goat farms. Epidemiology and Infection, 139(1), 19–26. doi:10.1017/S0950268810001032