This report describes the 4-year clinical outcomes of the SPIRIT II study, which randomized 300 patients to treatment with the XIENCE V everolimus-eluting stent (EES), or the TAXUS paclitaxel-eluting stent. At 4-year clinical follow-up, which was available in 256 (85.3%) patients, treatment with EES lead to a trend for lower rates of ischemia-driven major adverse cardiovascular events, a composite of cardiac death, myocardial infarction, and ischemia-driven target lesion revascularization (EES 7.7% vs. paclitaxel-eluting stent 16.4%, P = 0.056). Treatment with EES also resulted in a trend toward lower rates of cardiac death and numerically lower rates of myocardial infarction, ischemia-driven target lesion revascularization, and stent thrombosis. Overall, this study reports numerically fewer clinical events in patients treated with EES at 4-year follow-up, which is consistent with results from earlier follow-up. Copyright

Additional Metadata
Keywords angiography coronary (ANGO), diagnostic cardiac catheterization (CATH), percutaneous coronary intervention (PCI)
Persistent URL dx.doi.org/10.1002/ccd.22770, hdl.handle.net/1765/34494
Citation
Garg, S.A., Serruys, P.W.J.C., & Miquel-Hébert, K.. (2011). Four-year clinical follow-up of the XIENCE v everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: The SPIRIT II trial. Catheterization and Cardiovascular Interventions, 77(7), 1012–1017. doi:10.1002/ccd.22770