Background: Crohn's disease patients have a decreased Quality of Life (QoL) which is in part due to extreme fatigue. In a pilot study we prospectively assessed the feasibility and effect of psychological interventions in the management of fatigue. Methods: Patients with quiescent Crohn's disease and a high fatigue score according to the Checklist Individual Strength were randomized to Problem Solving Therapy (PST), Solution Focused Therapy (SFT) or to a control group (treatment as usual, TAU). Patients completed the Inflammatory Bowel Disease Questionnaire, the EuroQol-5D, and the Trimbos questionnaire for Costs. Results: Twenty-nine patients were included (12 TAU, 9 PST, 8 SFT), of these 72% were female, mean age was 31. years (range 20-50). The SFT group improved on the fatigue scale in 85.7% of the patients, in the PST group 60% showed improved fatigue scores and in the TAU group 45.5%.Although not significant, in both intervention groups the QoL increased. Medical costs lowered in 57.1% of the patients in the SFT group, in the TAU 45.5% and the in PST group 20%. The drop out rate was highest in the PST group (44%; SFT 12.5%; TAU 8.3%). Conclusions: PST and SFT both positively affect the fatigue and QoL scores in patients with Crohn's disease. SFT seems most feasible with fewer dropouts and is therefore a promising new tool in the management of fatigue in Crohn's disease patients.

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Keywords Costs, Fatigue, Inflammatory bowel disease, Problem solving therapy, Solution focused therapy
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Journal Journal of Crohn's and Colitis
Vogelaar, L, van 't Spijker, A, van Busschbach, J.J, Visser, M.S, Kuipers, E.J, & van der Woude, C.J. (2011). Solution focused therapy: A promising new tool in the management of fatigue in Crohn's disease patients. Psychological interventions for the management of fatigue in Crohn's disease. Journal of Crohn's and Colitis, 5(6), 585–591. doi:10.1016/j.crohns.2011.06.001