Phylogenetic evidence of canine distemper virus in Serengeti's lions.
Recently an epizootic, reported to be due to a morbillivirus infection, affected the lion population of the Tanzanian Serengeti National Park. A morbillivirus phosphoprotein (P) gene fragment was amplified by PCR from tissue samples of several affected lions. Sequencing of the amplificates and subsequent phylogenetic analyses revealed that a wild-type strain of canine distemper morbillivirus (CDV) was involved. Vaccination of the local domestic dog population with proven safe CDV vaccines is proposed.
|Keywords||Animals, Base Sequence, Comparative Study, Distemper Virus, Canine/*genetics, Distemper/prevention & control/virology, Dogs, Lions/*virology, Molecular Sequence Data, Morbillivirus/genetics, Phylogeny, Sequence Homology, Nucleic Acid, Tanzania|
|Persistent URL||dx.doi.org/10.1016/0264-410X(95)00024-U, hdl.handle.net/1765/3529|
Harder, T.C., Kenter, M.J.H., Appel, M.J.G., Roelke-Parker, M.E., Barrett, T., & Osterhaus, A.D.M.E.. (1995). Phylogenetic evidence of canine distemper virus in Serengeti's lions.. Vaccine, 13(6), 521–523. doi:10.1016/0264-410X(95)00024-U