2007-11-01
Mutation analysis of the BRAF oncogene in juvenile myelomonocytic leukemia
Publication
Publication
Haematologica , Volume 92 - Issue 11 p. 1574- 1575
Juvenile myelomonocytic leukemia (JMML) is a myeloproliferative/ myelodysplastic disorder associated with mutations in the Ras-Raf-MEK-ERK- signaling pathway. B-Raf plays a central role in this pathway. In 65 screened JMML patients we identified no BRAF mutations and we conclude that this gene is unlikely to play a role in the pathogenesis of JMML.
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| doi.org/10.3324/haematol.11493, hdl.handle.net/1765/36012 | |
| Haematologica | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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de Vries, A., Stam, R., Kratz, C., Zenker, M., Niemeyer, C., & van den Heuvel-Eibrink, M. (2007). Mutation analysis of the BRAF oncogene in juvenile myelomonocytic leukemia. Haematologica, 92(11), 1574–1575. doi:10.3324/haematol.11493 |
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