Interleukins, colony-stimulating factors and erythropoietin, together classified as hemopoietic growth factors, regulate the production of peripheral blood cells. These growth factors, which may act on developmentally early, immature bone marrow cells, or on late stages, i.e., on the maturation of committed progenitor cells, have been produced and purified to homogeneity as recombinant proteins. Several of these have entered phase I, II and HI clinical studies, whereas other are still under investigation in preclinical studies.
|Keywords||Bloedvorming, Diermodel, Interleukine-3, Interleukinen, Rhesusaap, Therapeutisch effect, hematologie, hemopoiesis , stem cells|
|Promotor||Bekkum, D.W. van|
van Gils, F.C.J.M.. (1993, December 15). Interleukin -3. Thesis Publishers. Retrieved from http://hdl.handle.net/1765/37803
|0977_Gils, Francisca Cornelia Johanna Maria van.jpg Cover Image , 78kb|
|stellingen Van Gils.pdf Other , 41kb|