2003-06-01
Genetic characterization of the unique short segment of phocid herpesvirus 1 reveals close relationships among alphaherpesvirusses of host of the order carnivora
Publication
Publication
Journal of General Virology , Volume 84 - Issue 6 p. 1427- 1430
To further characterize phocid herpesvirus type 1 (PhHV-1) at the molecular level, a cluster of genes comprising the complete unique short (Us) region of PhHV-1 has been cloned and sequenced. Within this region, ORFs were detected that code for the equivalent of the Us 2- protein of herpes simplex virus (HSV), a putative protein kinase, and for the glycoprotein equivalents gG, gD, gI and gE. In addition, two small ORFs downstream of gE, homologous to the Us 8·5 and Us 9 proteins of HSV were identified. Comparative analysis of the ORF encoding the gD equivalent of PhHV-1 identified the corresponding proteins of the alphaherpesviruses canine herpesvirus and, to lesser degree, feline herpesvirus as the closest relatives.
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doi.org/10.1099/vir.0.19005-0, hdl.handle.net/1765/3919 | |
Journal of General Virology | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Harder, T., Osterhaus, A., & Martina, B. (2003). Genetic characterization of the unique short segment of phocid herpesvirus 1 reveals close relationships among alphaherpesvirusses of host of the order carnivora. Journal of General Virology, 84(6), 1427–1430. doi:10.1099/vir.0.19005-0 |