This thesis is an investigation into the relationship between ferritin and haemosiderin, the major compounds in haemochromatosis, a genetic disorder leading to a severe disturbance of iron metabolism. In this study ferritins and ferritin-related compounds present in the livers of experimentally iron-loaded rats are analysed and compared, with each other and with haemosiderin. The results of this study will be preceded by a summary of iron metabolism