Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study.
The purpose of this study was to assess the safety and effectiveness of sirolimus-eluting stent (SES) postdilatation with largely oversized balloons. We evaluated the clinical outcome of 68 consecutive patients enrolled in the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry who underwent percutaneous coronary intervention with SES implantation and further postdilatation with balloons > 1 mm larger than the stent nominal size. Angiographic follow-up was either scheduled for selected subgroups or clinically driven. Overall, 75 lesions were treated. The procedure was successful in 98.5% of the cases. One patient (1.5%) underwent emergency coronary bypass surgery for acute vessel occlusion. During 10.1 +/- 1.7 months of follow-up, three patients (4.5%) died, one (1.5%) had acute myocardial infarction, and four (6%) had target vessel revascularization. At angiographic follow-up, loss index was 0.13 +/- 0.34 and restenosis rate was 7.7%. Although not routinely recommended in every patient, SES postdilatation with largely oversized balloons appears a safe and effective strategy for selected patients.
|Keywords||*Balloon Dilatation, *Coronary Angiography, *Stents, Aged, Blood Vessel Prosthesis Implantation, Coated Materials, Biocompatible/*therapeutic use, Coronary Disease/diagnosis/therapy, Coronary Restenosis/etiology/radiography/surgery, Equipment Design, Female, Follow-Up Studies, Humans, Immunosuppressive Agents/*therapeutic use, Male, Middle Aged, Myocardial Infarction/diagnosis/therapy, Netherlands/epidemiology, Platelet Glycoprotein GPIIb-IIIa Complex/therapeutic use, Postoperative Complications/etiology/radiography/surgery, Reoperation, Sirolimus/*therapeutic use, Treatment Outcome, Ultrasonography, Interventional|
|Persistent URL||dx.doi.org/10.1002/ccd.20001, hdl.handle.net/1765/4667|
Saia, F., Lemos, P.A., Arampatzis, C.A., Hoye, A., McFadden, E.P., Sianos, G., … de Feyter, P.J.. (2004). Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study.. Catheterization and Cardiovascular Interventions, 61(4), 455–460. doi:10.1002/ccd.20001