Although the thermogenic function of Brown Adipose Tissue (BAT) in hibernators has been recognized for many years, it has only been recently accepted that BAT is also the most important thermogenic organ in nonhibernators such as the rat. It has also become clear that thermogenesis in BAT does not only occur in response to cold but also in response to eating and that this does not occur in some obese animals. This chapter will desc~ibe some general aspects of BAT (lA) and review in short the physiological role of brown fat in thermogenesis (lB). The cellular changes that are involved in this process will be discussed (1 C) and some of the most important effects of various hormones in the brown adipocyte will be outlined (lD).

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Erasmus University Rotterdam
G. Hennemann (George) , P.R. Larsen (Reed)
hdl.handle.net/1765/51222
Erasmus MC: University Medical Center Rotterdam

Barge, R. (1987, October 2). Hormonal regulation and partial purification of thyroxine 5'-deiodinase in brown adipose tissue. Retrieved from http://hdl.handle.net/1765/51222