Coronary stent implantation represents a major advance in the treatment of obstructive coronary artery disease since the development of balloon angioplasty. However, in-stent restenosis (ISR) remains the most important limitation after stent implantation. An enormous number of studies had been devoted to the prevention of ISR. Attempts to reduce the risk of restenosis using different pharmacological and mechanical methods were unsuccessful. Recently, drug eluting stents (DES) have been emerged as a novel technology in reducing restenosis. In this thesis, we report the first clinical application of DES and detailed three dimensional intravascular ultrasound (IVUS) analysis after implantation of DES.

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Erasmus University Rotterdam
P.W.J.C. Serruys (Patrick) , P.J. de Feyter (Pim)
hdl.handle.net/1765/51349
Erasmus MC: University Medical Center Rotterdam

Degertekin, M. (2003, December 17). A new era in interventional cardiology: drug eluting first stents; clinical experience. Retrieved from http://hdl.handle.net/1765/51349