Abstract

Migraine is a neurovascular disorder characterized by a unilateral throbbing headache that lasts 4 to 72 hours and is often accompanied by nausea, vomiting, photo- and phonophobia. It has a prevalence of 8% in men and 20-25% in women. The exact mechanisms behind a migraine attack are not clear, but the trigeminovascular system seems to play a key role in the pathophysiology of migraine.

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A.H.J. Danser (Jan)
Erasmus University Rotterdam
Financial support by the Dutch Hearth Foundation for the publication of this thesis is gratefully acknowledged. Financial support of the following companies and institutions is gratefully acknowledged.: Menarini Farma Nederland Nederlandse Hoofdpijn Vereninging Glaxo Smith Kline
hdl.handle.net/1765/51662
Erasmus MC: University Medical Center Rotterdam

Labruijere, S. (2014, July 2). Neurovascular Pharmacology of Migraine: Epigenetics and Sex Hormones. Retrieved from http://hdl.handle.net/1765/51662