Endovascular photodynamic therapy (EPT), an adjunctive treatment modality to percutaneous transluminal angioplasty (PTA), was described. It is based on a light induced photobiochemical reaction of an accumulated photosensitizer in the artery. The results prove that EPT with 5-ALA inhibits balloon induced intimal hyperplasia effectively and is a promising adjuvant option in preventing intimal hyperplasia induced restenosis.

doi.org/10.1117/12.413698, hdl.handle.net/1765/52169
Clinical Lasers and Diagnostics
Department of Surgery

Gabeler, E. E. E., van Hillegersberg, R., Statius van Eps, R., Sluiter, W., Hayes, D., & van Urk, H. (2001). Endovascular photodynamic therapy inhibits intimal hyperplasia after PTA in a rat model. Presented at the Clinical Lasers and Diagnostics. doi:10.1117/12.413698