2013-10-31
A novel single compartment in vitro model: Perflurocarbons for electrophysiological studies of the rat urinary bladder
Publication
Publication
Presented at the
35th Annual International IEEE
EMBS Conference (July 2013), Osaka, Japan
This study presents a novel single compartment model for in vitro electrophysiological studies of the rat urinary bladder. We tested the functionality and suitability of FC-770 (a Perflurocarbon) for in vitro recording of nerve activity arising from the bladder in a single compartment setup. We have also favorably tested stimulation of the bladder via the bladder nerves in FC-770. The organ viability was monitored by recording spontaneous contractions of the bladder for a certain time. We propose the use of FC-770 as a fluid for nerve recording/stimulation in vitro as well as for maintaining organ viability, over the commonly used two compartmental methods.
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| doi.org/10.1109/EMBC.2013.6609783, hdl.handle.net/1765/52861 | |
| 35th Annual International IEEE EMBS Conference | |
| Organisation | Department of Urology |
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Choudhary, M., van Asselt, E., van Mastrigt, R., & Clavica, F. (2013). A novel single compartment in vitro model: Perflurocarbons for electrophysiological studies of the rat urinary bladder. Presented at the 35th Annual International IEEE
EMBS Conference. doi:10.1109/EMBC.2013.6609783 |
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