Can Thrombolysis prevent ischemic heart failure?
In the present era of thrombolysis, congestive heart failure secondary to (sub)acute coronary artery obstruction can be reduced to a considerable extent or even avoided altogether. Evidence from several recent trials in humans, aimed at restoring perfusion of the jeopardized myocardium-and thus preserving normal ventricular function-is presented. It is clear that thrombolysis, provided it is instituted within 4 h of onset of symptoms in patients with a large area of the myocardium at risk, can prevent ischemic heart failure.
|Keywords||0 (Fibrinolytic Agents), Clinical Trials, Coronary Thrombosis/drug therapy, Fibrinolytic Agents/*administration & dosage, Heart Failure, Congestive/*prevention & control, Human, Myocardial Infarction/complications/*drug therapy|
Simoons, M.L., & Hugenholtz, P.G.. (1988). Can Thrombolysis prevent ischemic heart failure?. Cardiology: international journal of cardiovascular medicine, surgery and pathology, 75(Suppl. 1), 90–102. Retrieved from http://hdl.handle.net/1765/5385