2014-04-01
Fully automated volumetric modulated arc therapy plan generation for prostate cancer patients
Publication
Publication
International Journal of Radiation: Oncology - Biology - Physics , Volume 88 - Issue 5 p. 1175- 1179
Purpose To develop and evaluate fully automated volumetric modulated arc therapy (VMAT) treatment planning for prostate cancer patients, avoiding manual trial-and-error tweaking of plan parameters by dosimetrists. Methods and Materials A system was developed for fully automated generation of VMAT plans with our commercial clinical treatment planning system (TPS), linked to the in-house developed Erasmus-iCycle multicriterial optimizer for preoptimization. For 30 randomly selected patients, automatically generated VMAT plans (VMAT auto) were compared with VMAT plans generated manually by 1 expert dosimetrist in the absence of time pressure (VMATman). For all treatment plans, planning target volume (PTV) coverage and sparing of organs-at-risk were quantified. Results All generated plans were clinically acceptable and had similar PTV coverage (V95% > 99%). For VMATauto and VMATman plans, the organ-at-risk sparing was similar as well, although only the former plans were generated without any planning workload. Conclusions Fully automated generation of high-quality VMAT plans for prostate cancer patients is feasible and has recently been implemented in our clinic.
Additional Metadata | |
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doi.org/10.1016/j.ijrobp.2013.12.046, hdl.handle.net/1765/54332 | |
International Journal of Radiation: Oncology - Biology - Physics | |
Organisation | Department of Radiation Oncology |
Voet, P. W. J., Dirkx, M., Breedveld, S., Al-Mamgani, A., Incrocci, L., & Heijmen, B. (2014). Fully automated volumetric modulated arc therapy plan generation for prostate cancer patients. International Journal of Radiation: Oncology - Biology - Physics, 88(5), 1175–1179. doi:10.1016/j.ijrobp.2013.12.046 |