2006-06-01
Epidemiology of Parkinson's disease
Publication
Publication
The Lancet Neurology , Volume 5 - Issue 6 p. 525- 535
The causes of Parkinson's disease (PD), the second most common neurodegenerative disorder, are still largely unknown. Current thinking is that major gene mutations cause only a small proportion of all cases and that in most cases, non-genetic factors play a part, probably in interaction with susceptibility genes. Numerous epidemiological studies have been done to identify such non-genetic risk factors, but most were small and methodologically limited. Larger, well-designed prospective cohort studies have only recently reached a stage at which they have enough incident patients and person-years of follow-up to investigate possible risk factors and their interactions. In this article, we review what is known about the prevalence, incidence, risk factors, and prognosis of PD from epidemiological studies.
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doi.org/10.1016/S1474-4422(06)70471-9, hdl.handle.net/1765/56129 | |
The Lancet Neurology | |
Organisation | Department of Neurology |
de Lau, L., & Breteler, M. (2006). Epidemiology of Parkinson's disease. The Lancet Neurology (Vol. 5, pp. 525–535). doi:10.1016/S1474-4422(06)70471-9 |