Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease
Serum levels of interleukin-6 (IL-6) were determined in 97 patients with clinically diagnosed Alzheimer's disease and 79 age- and sex-matched control subject. Median serum levels of IL-6 did not differ significantly between Alzheimer patients (8.6 U/ml) and controls (8.2 U/ml). Median levels of serum IL-6 were similar for sporadic and familial patients. The concentration of IL-6 was not associated with the severity of the dementia or the duration of the disease since first symptoms. According to these observations there is no evidence for a significant elevation in serum IL-6 in Alzheimer's disease.
|Keywords||0 (Interleukin-6), Aged, Alzheimer Disease/immunology, Human, Interleukin-6/blood, Middle Aged, Support, Non-U.S. Gov't, dementia|
van Duijn, C.M., Nagelkerken, L., & Hofman, A.. (1990). Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease. Neuroscience Letters, 108, 350–354. Retrieved from http://hdl.handle.net/1765/5781